Ultimately, the degree of immunocompromise for the patient is determined by the treating provider, and preventive actions should be tailored to each patient and situation.Other factors, such as end-stage renal disease, likely pose a lower degree of immunocompromise, and there might not be a need to follow the recommendations for those with moderate to severe immunocompromise.For the purposes of this guidance, moderate to severely immunocompromising conditions include, but might not be limited to, those defined in the interim clinical considerations for people with moderate to severe immunocompromise due to a medical condition or receipt of immunosuppressive medications or treatments.If a patient has persistently positive nucleic acid amplification tests beyond 30 days, additional testing could include molecular studies (e.g., genomic sequencing) or viral culture, in consultation with an infectious disease specialist.Re-testing for SARS-CoV-2 infection is suggested if symptoms worsen or return after ending isolation and precautions.Loss of taste and smell may persist for weeks or months after recovery and need not delay the end of isolation. Also, if a moderately or severely immunocompromised patient with COVID-19 was symptomatic, there should be resolution of fever for at least 24 hours (without the taking fever-reducing medication) and improvement of other symptoms.Results are negative from at least two consecutive respiratory specimens collected ≥ 24 hours apart (total of two negative specimens) tested using an antigen test or nucleic acid amplification test.
#28 WEEKS LATER ENDING EXPLAINED SERIAL#
The criteria for serial testing to end isolation are:.For these people, CDC recommends an isolation period of at least 20 days, and ending isolation in conjunction with serial testing and consultation with an infectious disease specialist to determine the appropriate duration of isolation and precautions. Moderately or severely immunocompromised patients may remain infectious beyond 20 days.Serial testing prior to ending isolation can be considered in consultation with infectious disease experts.įor people who are moderately or severely immunocompromised (regardless of COVID-19 symptoms or severity):.This may warrant extending the duration of isolation and precautions for up to 20 days after symptom onset (with day 0 being the day symptoms appeared) and after resolution of fever for at least 24 hours (without the taking fever-reducing medications) and improvement of other symptoms.
#28 WEEKS LATER ENDING EXPLAINED FULL#
Isolation should continue for at least 10 days after symptom onset (day 0 is the day symptoms appeared, and day 1 is the next full day thereafter).Isolation and precautions can be discontinued 10 days after symptom onset (day 0 is the day symptoms appeared, and day 1 is the next full day thereafter).įor people who are severely ill and not moderately or severely immunocompromised:.In certain high-risk congregate settings that have high risk of secondary transmission, CDC recommends a 10-day isolation period for residents.įor people who are moderately ill and not moderately or severely immunocompromised:.People who cannot wear a mask, including children If symptoms recur or worsen, the isolation period should restart at day 0.A test-based strategy may be used to remove a mask sooner. A high-quality mask should be worn around others at home and in public through day 10.
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